Source: ORISE | Release | August 25, 2017

Laboratory meets stringent inspection requirements for fifth time to retain continuous certification for 8 years.

A female scientist performs the beryllium lymphocyte proliferation test (BeLPT) at ORISE in Oak Ridge, Tenn.

The College of American Pathologists, or CAP, has accredited the Oak Ridge Institute for Science and Energy beryllium laboratory in Oak Ridge for the fifth time since the laboratory’s first accreditation in 2009. The laboratory is managed by ORAU for the U.S. Department of Energy.

The laboratory is one of only three labs nationwide that performs the beryllium lymphocyte proliferation test. This test determines if a patient has developed a sensitization to beryllium, which could evolve into chronic beryllium disease. Exposure to the lightweight metal is often encountered by inhaling beryllium dust particulates in an industrial workplace setting.

The biannual CAP accreditation process requires an onsite inspection of all procedures and processes as well as the laboratory’s records. During this process, inspectors thoroughly examine staff qualifications, equipment, facilities, safety program and record, and overall management. They follow lab personnel through each stage, from unpacking the blood specimens through the processing of these samples to the final analysis to determine if any of the samples show a sensitization to beryllium. The CAP accreditation program was established in the early 1960s and remains one of the most stringent lab certification programs recognized by the federal government.

In its letter announcing the continued accreditation, the CAP Accreditation Committee congratulated ORAU for its management of the beryllium laboratory and the excellence of the services that are provided.

“Attaining accreditation for the fifth time is a significant achievement for ORISE and reflects the staff’s commitment to continued excellence,” said the laboratory’s director, Donna Cragle, PhD and ORAU senior vice president. “Every day, our highly skilled team, led by our lab manager Ann Gehl, delivers the highest level of quality and a meticulous attention that our customers have come to expect from this facility.”

Inquiries regarding the test and how to access lab services can be sent to

College of American Pathologists

As the leading organization with more than 18,000 board-certified pathologists, the College of American Pathologists (CAP) serves patients, pathologists, and the public by fostering and advocating excellence in the practice of pathology and laboratory medicine worldwide. The CAP’s Laboratory Improvement Programs currently have customers in more than 100 countries, accrediting 7,700 laboratories and providing proficiency testing to 20,000 laboratories worldwide.

Find more information about the CAP at

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The Oak Ridge Institute for Science and Education (ORISE) is a U.S. Department of Energy (DOE) asset that is dedicated to enabling critical scientific, research, and health initiatives of the department and its laboratory system by providing world class expertise in STEM workforce development, scientific and technical reviews, and the evaluation of radiation exposure and environmental contamination.

ORISE is managed by ORAU, a 501(c)(3) nonprofit corporation and federal contractor, for DOE’s Office of Science. The single largest supporter of basic research in the physical sciences in the United States, the Office of Science is working to address some of the most pressing challenges of our time. For more information, please visit