Source: ORISE | Release | June 7, 2019

Lab increases capacity to meet more demand

The College of American Pathologists, or CAP, has accredited the Oak Ridge Institute for Science and Energy beryllium laboratory in Oak Ridge for the sixth time since the laboratory’s first accreditation in 2009.

The laboratory is one of only three labs nationwide that performs the beryllium lymphocyte proliferation test. This test determines if a patient has developed a sensitization to beryllium, which could evolve into chronic beryllium disease. Exposure to the lightweight metal is often encountered by inhaling beryllium dust particulates in an industrial workplace setting.

The biannual CAP accreditation process requires an onsite inspection of all procedures and processes as well as the laboratory’s records. During this process, inspectors thoroughly examine staff qualifications, equipment, facilities, safety program and its records, and overall management. They follow lab personnel through each stage, from unpacking the blood specimens through the processing of these samples to the final analysis to determine if any of the samples show a sensitization to beryllium.

“The CAP accreditation program remains one of the most stringent lab certification programs recognized by the federal government, and we are proud to have maintained our accreditation for the past 10 years as we continue to provide excellence in beryllium testing,” said the laboratory’s director, Donna Cragle, Ph.D., and ORISE director of health, environment and radiation management. “With the recent Occupational Safety and Health Administration’s stricter guidelines to beryllium permissible exposure limits for workers, our lab has increased our capacity in an effort to meet the anticipated demand of more requested tests.”

For more information on the ORISE beryllium testing lab, visit or email Barbara Neill at

For more information on the recent OSHA stricter beryllium guidelines for workers, visit:

 College of American Pathologists

As the leading organization with more than 18,000 board-certified pathologists, the College of American Pathologists (CAP) serves patients, pathologists, and the public by fostering and advocating excellence in the practice of pathology and laboratory medicine worldwide. The CAP’s Laboratory Improvement Programs currently have customers in more than 100 countries, accrediting 7,700 laboratories and providing proficiency testing to 20,000 laboratories worldwide.

Find more information about the CAP at

Follow CAP on Twitter: @pathologists.


The Oak Ridge Institute for Science and Education is a U.S. Department of Energy asset that is dedicated to enabling critical scientific, research, and health initiatives of the department and its laboratory system by providing world class expertise in STEM workforce development, scientific and technical reviews, and the evaluation of radiation exposure and environmental contamination. ORISE is managed by ORAU, a 501(c)(3) nonprofit corporation and federal contractor, for the U.S. Department of Energy’s Office of Science.

The U.S. Department of Energy’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time. For more information, visit