Source: Biospace.com | Release | April 10, 2019
Coquí Radio Pharmaceuticals Corp. is closer to realizing its goal of building a dedicated Medical Isotope Production Facility in Oak Ridge, Tennessee, after the U.S. Department of Energy (DOE) transferred land for the facility and provided research support through the national laboratories. Coquí’s facility will produce medical isotopes that diagnose and treat diseases, primarily Molybdenum-99 (Mo-99), which is used in 18 million medical procedures a year in the U.S. The DOE land transfer to Coquí of 206 acres in the Heritage Center Industrial Park places the company in a strategic location adjacent to federal research assets, Oak Ridge National Laboratory and the Y-12 National Security Complex.
Once fully operational, the facility will be the first of its kind in the U.S., which currently relies on imports to meet its Mo-99 needs. The most widely used medical isotope in the world, Mo-99 is relied on to diagnose and treat diseases including brain, heart, lung, liver, renal, oncologic, and muscle skeletal diseases.
“Coquí is best positioned to meet the demand for lifesaving medical isotopes because our technology is commercially proven and is used in the current supply chain,” said Carmen I. Bigles, founder and CEO of Coquí Radio Pharmaceuticals Corp. Design of Coquí’s facility is being led by INVAP, the world’s leading designer and developer of medical isotope production facilities. Coquí has an exclusive license with INVAP to use its technology in the United States.
Global supplies of Mo-99 are becoming increasingly unreliable as facilities capable of producing the isotope age and shut down. Mo-99 shortages, such as the one that occurred in November 2018, deprive patients from receiving lifesaving diagnostics and treatment. The U.S. currently has no domestic production source. The Coquí facility is expected to be fully operational in 2025 and will provide more than 200 high paying, permanent jobs.
“This land acquisition provides many advantages. Oak Ridge is home to several DOE and TVA nuclear facilities, providing a strong nuclear and engineering workforce. By growing our company in Oak Ridge we can leverage world-class research assets like Oak Ridge National Lab and the Y-12 National Security Complex,” added Bigles.
DOE has provided further support for the Coquí facility through research funding. These funds support Coquí’s partnership with Oak Ridge National Laboratory and the nearby Y-12 National Security Complex to conduct further research on Mo-99 target plate fabrication and qualification.
Coquí’s decision to locate its production facility in Oak Ridge makes its collaboration with Oak Ridge National Laboratory and the Y-12 National Security Complex easier and more efficient.
“This research partnership is critical and supports our efforts to obtain Nuclear Regulatory Commission and Food and Drug Administration approvals for the facility. The sooner we can begin producing U.S.-made Mo-99, the sooner we can minimize our dependency on foreign imports to meet critical U.S. medical needs,” said Bigles.
About Coquí Radio Pharmaceuticals Corp.
Coquí Pharma was founded in September 2009 with a mission to create a commercially scalable and reliable supply of Molybdenum-99, which is used in more than 18 million medical procedures to treat and diagnose disease each year in the U.S. For more information visit http://coquipharma.com/